Determination of toxic effects of deltamethrin on the primary gill cell culture of Lake Van fish [Alburnus tarichi (Güldenstadt 1814)]

Lake Van fish is one of few vertebrate species living in the lake, therefore it plays a very useful role as an indicator determining lake pollution. Deltamethrin (DLT) pesticides used extensively basin. In this study, was aimed to determine effects DLT on primary gill cell culture. Different concentrations (0.01, 0.1, 1, and 10 µM) were added culture total antioxidant oxidant levels, malondialdehyde (MDA), 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels determined at end 24 48 h administration. While highest concentration applied (10 caused significant increase level h, decrease detected (P < 0.05). The MDA level, which product lipid peroxidation unsaturated fatty acids, with 1–10 µM found be As result, can said that oxidative stress exposed 1 µM, but no genotoxic effect observed.